18.417 Introduction to Computational Molecular Biology

10/3/01

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Table of Contents

18.417 Introduction to Computational Molecular Biology

Intro to Molecular Biology

Computational Molecular Biology

Why Computational?

Intro to Molecular Biology

DNA: The double helix

DNA: the molecule of heredity

DNA: chemical details

DNA: deoxyribose sugar

DNA: the four bases

DNA: base pairs

DNA: sequences

DNA packaging

Chromosomes inside the cell

Intro to Molecular Biology

Genes control the making of cell parts

RNA: The messenger

From DNA to RNA: Transcription

From pre-mRNA to mRNA: Splicing

RNA can be functional

RNA structure: 2ndary and 3rdary

Splicing machinery

Intro to Molecular Biology

Proteins carry out the cell’s chemistry

Protein structure

Protein building blocks

From RNA to protein: Translation

The Genetic Code

The genetic code

Summary: The Central Dogma

Intro to Molecular Biology

RNA can make DNA

Protein can mediate inheritance

Non-mendelian inheritance rules

Evolutionary shortcuts

Combinatorial Bio-diversity

Our Goal

Author: Manolis Kamvysselis 

Email: manoli@mit.edu

Home Page: http://theory.lcs.mit.edu/~bab/01-18.417-home.html

Other information:
18.417 Fall 2001 Manolis Kamvysselis
For class use only 

References: Harvey Lodish et al., Bruce Birren, web resources